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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX8
All Species:
21.52
Human Site:
S456
Identified Species:
39.44
UniProt:
Q14562
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14562
NP_004932.1
1220
139315
S456
L
R
G
H
T
K
Q
S
M
D
M
S
P
I
K
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
A349
L
K
F
G
A
R
D
A
A
S
Q
E
P
K
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537627
1216
138553
S452
L
R
G
H
T
K
Q
S
M
D
M
S
P
I
K
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
S480
L
R
G
H
T
K
Q
S
M
D
M
S
P
I
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418105
1076
123154
M381
I
K
Q
I
A
A
N
M
R
G
I
G
M
M
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663993
1210
138002
S446
L
R
G
H
T
K
Q
S
M
D
M
S
P
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610928
1242
141917
L477
L
S
G
H
G
R
A
L
H
D
L
S
P
V
R
Honey Bee
Apis mellifera
XP_623289
1192
136394
L427
L
H
G
H
G
R
A
L
G
D
L
S
P
V
R
Nematode Worm
Caenorhab. elegans
Q09530
1200
135741
G428
L
R
G
Y
G
K
G
G
A
E
I
E
P
V
K
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
XP_002318357
1207
137837
S446
L
Q
G
Q
T
R
Y
S
V
D
V
S
P
V
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
S407
L
Q
G
Q
T
R
Y
S
V
D
M
S
P
V
K
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
D409
N
G
S
N
A
I
R
D
H
R
E
E
K
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40
N.A.
98.5
N.A.
96.8
N.A.
N.A.
N.A.
84
N.A.
91.1
N.A.
69.4
71.8
61.3
21.9
Protein Similarity:
100
59
N.A.
99.1
N.A.
97.3
N.A.
N.A.
N.A.
86.8
N.A.
94.5
N.A.
82
83.9
75.4
28.8
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
0
N.A.
93.3
N.A.
40
40
40
0
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
26.6
N.A.
100
N.A.
66.6
66.6
66.6
0
Percent
Protein Identity:
59.1
N.A.
N.A.
59.3
44.2
N.A.
Protein Similarity:
75
N.A.
N.A.
75.4
62.8
N.A.
P-Site Identity:
53.3
N.A.
N.A.
60
0
N.A.
P-Site Similarity:
86.6
N.A.
N.A.
86.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
24
8
16
8
16
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
8
0
62
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
8
24
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
70
8
24
0
8
8
8
8
0
8
0
0
0
% G
% His:
0
8
0
47
0
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
0
0
0
0
16
0
0
24
0
% I
% Lys:
0
16
0
0
0
39
0
0
0
0
0
0
8
8
54
% K
% Leu:
77
0
0
0
0
0
0
16
0
0
16
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
8
31
0
39
0
8
8
0
% M
% Asn:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
77
0
8
% P
% Gln:
0
16
8
16
0
0
31
0
0
0
8
0
0
0
0
% Q
% Arg:
0
39
0
0
0
39
8
0
8
8
0
0
0
0
24
% R
% Ser:
0
8
8
0
0
0
0
47
0
8
0
62
0
0
0
% S
% Thr:
0
0
0
0
47
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
16
0
8
0
0
47
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
16
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _